20 years in microbiome support

Most probiotics on the market do not really survive stomach and pancreas passage.

Most probiotics on the market do not really survive stomach and pancreas passage.

Indeed, the use of a lyophilized powder does not offer a protection to the bacteria, and therefore get damaged.

Lactobact use Intelicaps® a new dimension to probiotic microencapsulation.

  • ​Intelicaps®, a new and patented technology, uses a very gentle extrusion process and a proprietary mix of biopolymers.
  • The microcapsules are then very stable, capable to resist to increased heat, low pH, moisture and increased oxygen concentrations.
  • Resistant to low pH values.
    • They resist to 80%+ at pH <2 after 2 hours when classic lyophilized probiotics achieve only less than 8%.
    • They only open in the intestinal tract at a pH >6,5. ​​​
  • Resistant to elevated storage temperatures.
  • Very high survival rate of the bacterial cultures during the stomach and duodenum passage.
Lactobact use Intelicaps® a new dimension to probiotic microencapsulation.

Compared to most probiotics, Lactobact® Intelicaps® selected SHIME® one of the few gut models to demonstrate the efficacy of the protection capability of the new microencapsulation.

The SHIME® model (Simulator of the Human Intestine Microbial Ecosystem) is the sole in vitro model that integrates the entire gastrointestinal transit into one system.

The SHIME® model (Simulator of the Human Intestine Microbial Ecosystem) is the sole in vitro model that integrates the entire gastrointestinal transit into one system.

  • Unlike the large majority of gut models, the SHIME® mimics the entire gastrointestinal tract incorporating stomach, small intestine and different colon regions.
  • The SHIME® brings unique capabilities to study physicochemical, enzymatic and microbial parameters in the gastrointestinal tract in a controlled in vitro setting.
  • The SHIME® set-up leads to an accurate and relevant simulation of the targeted human host.

Typically, a SHIME® experiment consists of 4 stages:

  1. a stabilization period (2 weeks) to allow adaptation of the microbial community to the environmental conditions in the respective colon regions.
  2. a basal period (2 weeks) in which the reactor is operated under nominal conditions and baseline parameters are measured.
  3. a treatment period (2–4 weeks) where the effect of a specific treatment on the gastrointestinal microbial community is tested.
  4. a washout period (2 weeks) to determine how long the changes induced by the tested substance can still be measured in the absence of the substance itself.

This is interesting to study for example digestibility of prebiotic substrates and its subsequent fermentability in the colon or the survival of pathogens or probiotics in the upper digestive tract before they reach the colon environment.

This approach has mainly been used to investigate the activity and stability of probiotics and prebiotics during gastrointestinal transfer, the microbial conversion of bioactive food components (e.g. phytoestrogens), the metabolism of pharmaceutical components, the efficacy of colonic targeted delivery systems and the conversion and biological (in)activation of food and/or ingested environmental contaminants.

30 years of accumulated Know-how

30 years of accumulated Know-how

Since 1993

Unique scientifically validated dynamic model.

160 peer-reviewed scientific publications.

<p>SHIME® simulates both the upper and lower GT</p>
<li>The upper (stomach, small intestine)</li>
<li>The lower (ascending, transverse, descending) colon regions</li>
<p>SHIME® mimics the conditions in all colon regions</p>

Entire gastroentestinal transit

SHIME® simulates both the upper and lower GT

  • The upper (stomach, small intestine)
  • The lower (ascending, transverse, descending) colon regions

SHIME® mimics the conditions in all colon regions

  • Ascending
  • Transverse
  • Descending
<p>SHIME® covers the pH variety and complexity.</p>
<p>The gastric compartment works at a fixed pH of 2.0</p>
<p>The small intestine compartment typically operates at slightly acidic to neutral conditions</p>
<p>The pH of the colon compartments is controlled between</p>
<li>5.6 – 5.9 in the ascending</li>
<li>6.1 – 6.4 in the transverse</li>
<li>6.6 – 6.9 in the descending colon.</li>

Each pH condition

SHIME® covers the pH variety and complexity.

The gastric compartment works at a fixed pH of 2.0

The small intestine compartment typically operates at slightly acidic to neutral conditions

The pH of the colon compartments is controlled between

  • 5.6 – 5.9 in the ascending
  • 6.1 – 6.4 in the transverse
  • 6.6 – 6.9 in the descending colon.
<p>SHIME® brings the possibility of simulating the microbiome from different human target groups e.g</p>
<li>Adult vs. infant,</li>
<li>Healthy vs. diseased</li>

Human target groups

SHIME® brings the possibility of simulating the microbiome from different human target groups e.g

  • Adult vs. infant,
  • Healthy vs. diseased

Lactobact BABY+


0 to 2 years

  • 3 selected bacterial cultures
    • Bifidobacterium bifidum
    • Bifidobacterium breve
    • Lactobacillus casei
  • Builds up immunity
  • Prevents colics
  • Supports constipation and bloating relief
  • Promotes balance during and after antibiotic intake.
  • Folic acid supports maternal tissue growth during pregnancy
  • ​To be stirred into the bottle or mushy food.
  • No activation time. A direct consumption is possible.
  • They are protected from oxidation and moisture.
  • No refrigeration needed.

Lactobact JUNIOR+


2 years to 8 years

  • 6 selected bacterial cultures
    • Bifidobacterium bifidum
    • Bifidobacterium breve
    • Bifidobacterium lactis
    • Lactobacillus casei
    • Lactobacillus plantarum
    • Streptococcus thermophilus
  • Restores intestinal flora
  • Relieves constipation
  • Folic acid (Vit B9) supports the immune system
  • Pantothenic acid (Vit B5) helps reduction of fatigue.
  • ​Direct consumption.
  • No activation time needed.
  • To be stirred into drinks, food.
  • They are protected from oxidation and moisture.
  • No refrigeration needed.

Lactobact PREMIUM


8 years+ children, teenagers, adults

  • The daily dose of 1 capsule contains

    • B.animalis subsp. lactis B.breve B. adolescentis B. longum B. bifidum

    • L. acidophilus L. casei L. paracasei L. plantarum L. rhamnosus
    • Streptococcus thermophilus
    • 50 mg inulin
  • Synbiotic prebiotic and probiotic
  • 11 strains, 8bn
  • Vegetable dietary fibre inulin
  • Slow release vegan capsule
  • 8 years+, teenager, adult
  • 1 time x 1 capsule with meal
  • 30 capsules, 1 month
  • ​The cellulose capsules can be removed and the micro-encapsulated powder stirred into drinks and food.(The micro-encapsulated powder combined with an additional cellulose capsule offer double protection for patients having difficulty in swallowing capsules).

Lactobact AAD


8 years+ children, teenagers, adults

  • Bifidobacterium lactis
  • Bifidobacterium longum
  • Enterococcus faecium
  • Lactobacillus acidophilus
  • Lactobacillus salivarius
  • counteracts growth of pathogenic germs
  • boosts development of healthy intestinal flora
  • optimizes the acid base balance in the gut
  • prevents and reduces side effects related to antibiotic
  • Prevention of Antibiotic-Associated Diarrhea
  • During and after antibiotic treatment

Frequently asked questions

  • No. Our Lactobact® probiotics are shelf stable and don’t need refrigeration.

  • In the intestine live many small microorganisms and form the so-called intestinal flora . It consists of countless good bacteria. An antibiotic works against bacteria. Frequently, so-called broadband antibiotics are used. In other words, they are not specifically geared to a type of bacteria and destroy not only the bad bacteria but also the good intestinal bacteria. As a result, pathogenic germs in the gut can spread, such as clostridia . These cause strong diarrhea after taking antibiotics. Diarrhea during or after antibiotic therapy is also called antibiotic- associated diarrhea (AAD).

  • The Clostridia , which are located in the intestinal flora , ensure diarrhea when taking antibiotics. Depending on how fast these bacteria multiply, diarrhea associated with antibiotic therapy may occur after one to two days . In the worst case, diarrhea persists for up to 2 weeks after taking the antibiotic . In general, a gut flora can recover from the clostridia and return to normal equilibrium. This can take up to a year.

  • The more antibiotics and especially broad-spectrum antibiotics are taken, the greater the damage in the balanced intestinal flora . Harmful germs like Clostridia can spread more and more and this leads to diarrhea after taking antibiotics. If the intestinal flora can not recover, it can not only cause digestive problems. Vitamins and other nutrients can no longer be absorbed properly by the intestine. The immune system, which is 80% in the intestine, can get out of joint. Incompatibilities are the result. This often results in allergies, such as hay fever.

  • In order to rebuild the complex and diverse intestinal flora , one needs a probiotic agent containing several selected bacterial strains. In addition, it should be high doses, as antibiotics repeatedly kill bacteria in the gut. Therefore, the agent Lactobact® AAD is recommended for diarrhea caused by antibiotics . The remedy should be taken already during the therapy with the antibiotic, however, within a temporal distance of approx. 2 hours. After antibiotic therapy, the agent Lactobact® PREMIUM is recommended for the long-term development of a complex intestinal flora .

  • If no additional means of intestinal florasanation are taken, the intestine needs at least 6 weeks, but in many cases up to a year to fully recover. It depends on the individual and their lifestyle. With additional intake of Lactobact® AAD to the antibiotic and a subsequent 4 weeks cure with Lactobact® PREMIUM , the intestinal flora is then largely built up. The likelihood of diarrhea with antibiotics being taken with the medication is thus reduced by 90%.

  • Yes

  • Intestinal flora is the term for a multiplicity of bacteria which live in our intestine. They are on the mucus layer lining the intestine. The bacteria in the intestine bring a weight of about 1-2 kgs on the scales. Their tasks are vital to the body. For example, they are involved in enzyme and vitamin formation and in the breakdown of plant compounds that we otherwise would not digest. In addition, our intestinal flora communicates with the immune system and supports the formation of anti-inflammatory messengers. The protection against pathogens also comes from the intestinal flora.

  • A disturbed intestinal flora is called dysbiosis in medical parlance. This means that pathogenic bacteria in the intestine could multiply many times. This leads to an altered bacterial colonization. The consequences of a disturbed intestinal flora can not only be diarrhoea, constipation and flatulence, but also inflammatory diseases occur. If it comes to a dysbiosis, you can with a balanced, high-fiber diet, exercise and with probiotics preparations to rebuild the intestinal flora.

  • A disturbance of the intestinal flora can come about through various causes. An unbalanced diet high in fat, sugar, and low fiber negatively affects the intestinal flora composition. Also, the factor of movement plays a major role for a balanced healthy bacterial composition in the intestine. Antibiotics are a common problem. Antibiotics have to be taken for some diseases, but unfortunately they not only kill pathogenic bacteria but also kill our healthy intestinal bacteria. Babies often suffer from disturbed intestinal flora if they are born by caesarean section or are not breastfed.

  • “Probiotics are living microorganisms that, when consumed in adequate numbers, have a health effect on the host,” is the WHO / FAO definition of probiotic intestinal bacteria since 2001. This means that probiotic gut bacteria must meet specific requirements. First and foremost, it is important that the bacteria survive the gastric and bile acids without damage. Because unprotected strains of bacteria can lose their viability within a very short time and thus become ineffective. The products should also be present in high concentrations.

  • There are a variety of probiotic bacterial strains with clinical evidence in the gastrointestinal tract. In medical use, the following probiotic species are predominantly used: lactobacilli , bifidobacteria , Enterococcus faecium and Escherichia coli. A combination of selected probiotic intestinal bacteria in high concentration ensures the desired health effect.

  • There is now a wealth of clinical study material on the administration of probiotic intestinal bacteria . Probiotic intestinal bacteria are used at any age. In babies born as cesarean birth or not breastfed, it was found that the intestinal flora is different in composition compared to vaginal birth and nursing children. When occurring three-month colic also like probiotics are used. Older children are often affected by asthma, allergies and atopic dermatitis or antibiotics cause a shift in the intestinal flora . Meanwhile, diseases of the nervous system are increasingly in the focus of the researchers, in which a maloccupation of the intestinal flora seems to play a role

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